1-[4-(methylsulfonyl)phenyl]ethanone
4'-Methylsulfonylacetophenone
CAS: 10297-73-1
Molecular Formula: C9H10O3S
1-[4-(methylsulfonyl)phenyl]ethanone - Names and Identifiers
| Name | 4'-Methylsulfonylacetophenone |
| Synonyms | 4'-Mesylacetophenone 4-methylsulfonylacetophenone 4-Methylsulphonylacetophenone 4'-Methylsulfonylacetophenone 4-Methylsulphonyl Acetophenone (4-Methanesulphonylphenyl)-ethanone 1-(4-(methylsufonyl)phenyl)ethanone 1-[4-(methylsulfonyl)phenyl]ethanone Ethanone, 1-[4-(methylsulfonyl)phenyl]- 4-Methyi Sulfonyl Acetophenone, Rofecoxib, |
| CAS | 10297-73-1 |
| EINECS | 233-672-0 |
| InChI | InChI=1/C9H10O3S/c1-7(10)8-3-5-9(6-4-8)13(2,11)12/h3-6H,1-2H3 |
1-[4-(methylsulfonyl)phenyl]ethanone - Physico-chemical Properties
| Molecular Formula | C9H10O3S |
| Molar Mass | 198.24 |
| Density | 1.3339 (rough estimate) |
| Melting Point | 126-129°C(lit.) |
| Boling Point | 305.56°C (rough estimate) |
| Flash Point | 242°C |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 3.82E-06mmHg at 25°C |
| Appearance | yellowish-like powder |
| Color | White to slightly yellow |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5250 (estimate) |
| MDL | MFCD00025072 |
1-[4-(methylsulfonyl)phenyl]ethanone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29144000 |
| Hazard Class | IRRITANT |
1-[4-(methylsulfonyl)phenyl]ethanone - Introduction
4-methylsulfonylacetophenone, the chemical formula C8H9KS, is also known as Methylthone. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 4-Methylsulfonylacetophenone is a colorless to pale yellow solid.
-Solubility: It is soluble in common organic solvents (such as ethanol, acetone, chloroform).
-Stability: It is unstable and can decompose or trigger combustion.
-lethal dose: toxic to the human body, fatal.
Use:
-Laboratory research purposes: 4-methylsulfonyl acetophenone can be used as an intermediate in organic synthesis reactions, including drug synthesis, perfume synthesis and other fields.
-Stimulant: Due to its structural similarity to the drug MDMA, 4-methylsulfonylacetophenone may be misused as a banned drug to achieve similar stimulatory or hallucinogenic effects.
Preparation Method:
A commonly used preparation method is to react acetophenone and 4-methylsulfone under the catalysis of hydrochloric acid to obtain 4-methylsulfonyl acetophenone.
Safety Information:
-Irritating to eyes and skin, rinse with plenty of water immediately after contact.
-Inhalation of this substance can cause respiratory irritation. Ensure good ventilation and respiratory protection equipment.
- 4-methyl sulfonyl acetophenone is a flammable substance, avoid contact with heat sources, to prevent sparks, fire caused by combustion or explosion.
-Due to the potential risk of abuse, the use, storage and distribution of 4-methylsulfonylacetophenone should be subject to national and local laws and regulations to ensure safe use.
Nature:
-Appearance: 4-Methylsulfonylacetophenone is a colorless to pale yellow solid.
-Solubility: It is soluble in common organic solvents (such as ethanol, acetone, chloroform).
-Stability: It is unstable and can decompose or trigger combustion.
-lethal dose: toxic to the human body, fatal.
Use:
-Laboratory research purposes: 4-methylsulfonyl acetophenone can be used as an intermediate in organic synthesis reactions, including drug synthesis, perfume synthesis and other fields.
-Stimulant: Due to its structural similarity to the drug MDMA, 4-methylsulfonylacetophenone may be misused as a banned drug to achieve similar stimulatory or hallucinogenic effects.
Preparation Method:
A commonly used preparation method is to react acetophenone and 4-methylsulfone under the catalysis of hydrochloric acid to obtain 4-methylsulfonyl acetophenone.
Safety Information:
-Irritating to eyes and skin, rinse with plenty of water immediately after contact.
-Inhalation of this substance can cause respiratory irritation. Ensure good ventilation and respiratory protection equipment.
- 4-methyl sulfonyl acetophenone is a flammable substance, avoid contact with heat sources, to prevent sparks, fire caused by combustion or explosion.
-Due to the potential risk of abuse, the use, storage and distribution of 4-methylsulfonylacetophenone should be subject to national and local laws and regulations to ensure safe use.
Last Update：2024-04-09 02:00:40
![1-[4-(methylsulfonyl)phenyl]ethanone](http://res.chembk.com/assets/str/2d/1/10/10297-73-1.png)
Supplier List
Featured ProductsSpot supply
Product Name: 4-Methylsulphonylacetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Featured Products
Product Name: 4'-Methylsulphonylacetophenone Request for quotationCAS: 10297-73-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Spot supply
Product Name: 4'-(Methylsulfonyl)acetophenone Request for quotationCAS: 10297-73-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Methylsulphonylacetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4'-(Methylsulfonyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4-(Methyl suifonyl) acetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-(Methylsulfonyl)Acetophenone Visit Supplier Webpage Request for quotation
CAS: 10297-73-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 10297-73-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 4-Methylsulphonylacetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Featured Products
Product Name: 4'-Methylsulphonylacetophenone Request for quotationCAS: 10297-73-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Spot supply
Product Name: 4'-(Methylsulfonyl)acetophenone Request for quotationCAS: 10297-73-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Methylsulphonylacetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4'-(Methylsulfonyl)acetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 4-(Methyl suifonyl) acetophenone Visit Supplier Webpage Request for quotationCAS: 10297-73-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-(Methylsulfonyl)Acetophenone Visit Supplier Webpage Request for quotation
CAS: 10297-73-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 10297-73-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History